Athena Enzyme Systems
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Protein Expression | Cell Culture Products | Specialty Proteins |  Enzyme Assays | Manufacturing Services

Flex-JIT™ - Custom
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Manufacturing Services

Flex JIT™ - A Flexible, Cost-effective Manufacturing Service

FlexJIT™ is a flexible just-in-time manufacturing service.  AthenaES has developed an efficient manufacturing process for producing liquid and powder products that is both flexible and responsive, which allows our manufacturing team to rapidly adapt to any variable production needs and schedules of our clients.  We produce liquid and dry powder culture media as well as an array of chemical and biological reagents for the life science industry.  From simple 2 component products to complex 80 component chemical-biological mixtures, Athena produces a wide range of products in batch sizes from milligrams to kilograms and liters to hectoliters.  We partner with early-staged as well as established life science companies to support them in establishing a customized and comprehensive, low-cost and low-risk manufacturing capability.
Benefits
  • Reduced Upfront Costs:
    • No need to invest in or maintain product inventory when sales are uncertain.
    • Lower initial capital costs, de-risks infrastructure costs.
  • Market Responsive:
    • Rapid turnaround for on-the-fly adjustable batch sizes and schedule to match product sales.
    • Provides surge capacity when sales increase rapidly.
  • Comprehensive Support:
    • Complete logistic support and supply chain security from raw materials to delivery to your customer.
    • Experienced experts in the manufacture of life science products.
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Capabilities Statement

flex-jit_capabilities_voct20.pdf
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Contact Us

Tel. (in US and Canada): 888-892-8408
Tel. (International): +1 410-455-6319
Email: Click here.

Cell Culture Media

​Athena offers an array of custom cell culture formulations including generic media such as RPMI, DMEM, EMEM, McCoy’s 5A, etc. as well as our proprietary cell culture media with custom alterations.  We can tailor formulations to include or exclude select amino acids like arginine, lysine, leucine, and methionine, with or without high or low levels of glucose, or with and without any other component.  Orders can be made to fit any research requirements, including SILAC experiments, production of recombinant proteins and animal-product-free applications.  Bulk or small-batch orders are available with a minimum purchase of 5 L.

Dry Powder Manufacturing

Athena can produce most media and buffer formulations as a dehydrated medium.  Dehydrated blends of media and buffers have a longer shelf-life and lower unit cost for shipping.  Storage and transportation are at ambient temperatures thereby eliminating the need for expensive cold-chain shipment and storage under refrigerated conditions.  Athena does custom packaging in single use packets, gram to kilogram bottle containers, or multi-kilogram drums depending on the customer’s need. 

OEM and Private Labeling

OEM and private labeling services are available for generic or customer-defined media formulations.  AthenaES provides custom manufacturing and packaging to support customer’s production needs.  Production schedules and batch sizes are flexible allowing for agile supplies based on demand.  Logistical support is available for further inventory control and support of our partner’s customers.
  • Formulation Design and Testing
  • Quality Control Test Design, Development, and Validation
  • Pre-Launch Pilot Production
  • Commercial-scale Manufacturing 
  • Small-scale Batches
  • SILAC Media Formulation 
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Custom Contract Services

​Protein Expression

Athena specializes in optimizing recombinant protein expression systems to maximize yield and purity. We concentrate on expressing difficult-to-produce proteins that have the potential to provide ground-breaking benefits. Our capabilities and support meet the needs of industry, academic, and government
researchers from small-scale technical and commercial feasibility studies to final product manufacturing. With the advent of Athena’s ACESTM (AthenaESTM Complete Expression System) and the use of the revolutionary YebF protein, we can tackle a wide range of proteins that may be unable to be expressed under normal conditions.

Biocatalyst Development

Athena’s biocatalyst development employs an array of techniques to identify and optimize biocatalytic activity for industrial processes. AthenaESTM can screen a wide range of microbes for
specific enzymatic activity, determine the source of an enzyme and optimize the enzyme activity for substrate specificity.
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  • Gene Cloning and Expression Vector Construction
  • Cell Line Engineering and Media Optimization
  • Purification Process Development 
  • Quality Control Test Development and Validation
  • Product Characterization for Identity, Purity, and Potency
  • Finished Products Formulation 
  • Stability Analysis
  • Bench and Pilot scale Production

Our Team

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​Sheldon E. Broedel, Jr., Ph.D.
Chief Executive and Science Officer

Ph.D., UMBC, 1990
M.S., UMBC, 1984
B.S., SUNY Geneseo, 1979
​

Biographical Sketch:
Dr. Broedel is a founder of Athena Environmental Sciences, Inc. and has served as CEO/CSO since the company’s inception in 1994.  He also holds a position as the Associate Graduate Program Director and Adjunct Professor for the MPS in Biotechnology at UMBC and an Adjunct Professor with the Department of Microbiology and Immunology at Georgetown University School of Medicine.  Dr. Broedel serves on several boards including founding Chairman of the Science Advisory Board for the College of Natural and Mathematical Sciences at UMBC (2007-2009), Board Member of the Science Advisory Board to Stevenson University (2009-Present), Advisory Board Member of the MPS in Biotechnology Program UMBC (2007-Present), Scientific Advisory Boards for Applied Cell Sciences, Inc. (2007-2009), Plasmonix (2014-2016) and GlycoPure (2016-Present).  Dr. Broedel received his doctoral and master's degrees from the University of Maryland Baltimore County in Microbial and Molecular Genetics and his B.S. degree in Biology from the State University of New York at Geneseo.  He has 30 years of industrial experience, which included positions with Martin Marietta Laboratories, Dorlin Pharmaceuticals, Inc. (formerly ChekTec Corporation) and Athena Environmental Sciences, Inc. as well as 8 years of post-graduate academic research experience.  In 2005, Dr. Broedel received UMBC’s Outstanding Alumni of the Year Award.  Dr. Broedel has a diverse range scientific publications, holds several issued patents, and has designed, reduced to practice and launched more than 160 products ranging from life science research tools to consumer products.  He and his development teams have received eleven SBIR grant awards for their work with infectious diseases, bioprocessing and diagnostic tests.  His technical expertise and experience includes microbiology, genetics, molecular biology, immunochemistry, biochemistry and enzymology, drug discovery and high throughput screening, fermentation and process development, and GLP/GMP manufacturing of biologics. 


© Copyright, 2022 Athena Environmental Sciences, Inc.
Phone: 410-455-6319
Fax: 410-455-1155

  • Home
  • Products
    • Protein Expression > >
      • Expression Media > >
        • Optimization Kits
        • LB and APF LB Broth
        • Turbo and Turbo Prime Broth
        • Superior and Superior Prime Broth
        • Power and Power Prime Broth
        • Hyper Broth
        • Glucose M9Y
        • Atholate
        • Augmedium ​and LB Booster
      • Protein Refolding
      • Examples
    • Cell Culture > >
      • NEW! Classical Media
      • Serum-free Media > >
        • BRFF-BMZERO
        • BRFF-EPM2
        • BRFF-HPC1
        • ​BRFF-P4-8F
        • DMEM / F12 Serum-Free Medium
        • IMDM Serum-Free Medium
        • SFM Screening Kit
      • Accessory Products > >
        • FNC Coating Mix
        • Freezing Media Pair
        • PET
        • Bovine Pituitary Extract
        • Hepes Buffered Saline
        • Waymouth Cryopreservation Medium
        • L-Alanyl-L-Glutamine
      • Custom Medium Mfg
      • SILAC Media
      • Stem Cells
    • Specialty Proteins
    • Enzyme Assays
    • Manufacturing Services >
      • Biochromatography
  • Support
  • Contact
  • Order Page
    • Distributors